Director Translational Sciences – Nonclinical Pharmacology
Please be aware that Acadia has a mandatory COVID-19 vaccination policy for all employees.
Responsible for the oversight of Translational Biosciences preclinical deliverables with a clear understanding of functional interdependencies and critical path activities. The role will supply to the research and/or development of the products, projects, and programs in support of the pipeline. Leads conduct and collaborate on basic research and development focusing on pre-clinical pharmacology, pharmacodynamic and translational pharmacology, target validation, neuro behavioral models, mechanism of action, and CNS drug discovery studies supporting various projects relevant to the long-term objectives of the organization. The role provides scientific study management support for preclinical programs and is accountable for working across functional areas on projects in a timely and efficient way. Facilitating communication of project status and issues, and developing strategies to ensure project team goals and deliverables are met.
- Oversees the management of Translational Biosciences deliverables with a focus on preclinical research and development!
- Establishes strategies and experimental programs necessary to investigate key lines of scientific inquiry important to the business objectives, as outlined in the company's strategic business plan and particular department goals
- Plans CNS-focused experimental programs focusing on preclinical pharmacology, pharmacodynamic and translational pharmacology, target validation, mechanism of action, and lead optimization, to include design, logistics, resource allocation, schedules, identified critical support needs, and other necessary details to support the program(s)
- Leads vendors and consultants to complete Translational Biosciences studies for the various programs
- Provides cross-functional study management support for preclinical programs including the development and management of timelines and leading regular team meetings!
- Helps support the preparation of reports and regulatory documents for IND and NDA submissions
- Supports due diligence projects by defining nonclinical study plans and compound requirements and developing overall project timelines and associated budgets
- Works cross-functionally including initiating/attending sub-team meetings and coordinating ad hoc working for groups as needed to move project activities forward
- Leads all aspects of a compilation of Project Team documents associated with all areas of development
- Provides mentorship to team members to objectively assess and resolve project issues to improve project efficiency
- The ideal candidate will possess a Ph.D. in pharmacology, neuroscience or a relevant subject area.
- Desired 5-10 years of dynamic experience in industrial pre-clinical R&D.
- Experience in Translational Biosciences activities with an emphasis on preclinical discovery R&D.
- A sophisticated understanding of neuroscience principles, preclinical neuro-behavioral models of CNS disorders, and standard neuroscience research techniques
- Hands-on experience with preclinical research, in-vitro and in vivo testing to drive drug discovery and development
- In-depth experience with the drug development process and the principles, concepts, practices, and standards of pharmaceutical project management
- Validated experience generating and authoring scientific research manuscripts and reports for internal use and external publication
- Experience producing and authoring preclinical pharmacology regulatory documents including FDA briefing documents, preclinical pharmacology summaries, Investigator’s brochures, IND submissions, NDA and ANDA submissions
- Ability to establish and cultivate relationships with scientific and R&D communities in the pharmaceutical and biotech community as well as academic communities within the scope of company therapeutic focus and product development interests.
- Comfortable in a results-oriented, project-driven, real-time team environment, prioritize projects and deliver quality results within tight time constraints.
- High degree of accuracy and attention to detail.
- Ability to think strategically as well as to act tactically and proactively.
- Experience handling cross-functional project teams and working in a semi-virtual environment including CROs and academic collaborations.
- Demonstrated skills and abilities in coaching, influencing, facilitation, development, and problem solving
- Excellent communication, presentation, consultative, partnership, and interpersonal skills.
- Ability to elicit collaboration from a wide variety of sources and to be persuasive, encouraging, and motivating
- Ability to learn, understand and apply new technologies, strategies and approaches that enhance the team’s ability to achieve goals and meet timelines/deliverables
- Proficient at crafting and communicating a clear vision among team members efficiently aligning resources and activities to achieve functional area and/or interpersonal goals
Establishes strategic plans for designated function(s) and may participate in management to align objectives across the organization. Develops methods, techniques, and evaluation criteria for projects, programs, and people. Works on sophisticated issues where analysis of situations or data requires an in-depth knowledge of the functional area and related interpersonal objectives. Erroneous decisions will have a serious impact on the overall success of the functional area and may impact the long-term success of the company.
While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk or hear in a standard office environment. The employee must occasionally lift and/or move up to 15 pounds. Ability to travel by car or airplane independently up to 25% of the time and work after hours if required by travel schedule or business issues.
What we offer you:
- Competitive base, bonus, new hire and ongoing equity packages
- Medical, dental, and vision insurance
- 401(k) Plan with a fully vested company match 1:1 up to 5%
- Employee Stock Purchase Plan with a 2-year purchase price lock-in
- 15+ vacation days
- 14 paid holidays plus one floating holiday of your choice, including office closure between December 24th and January 1st
- 10 days of paid sick time
- Paid parental leave
- Tuition assistance
Studies have shown that women and people of color are less likely to apply for jobs unless they believe they meet every single one of the qualifications in the exact way they are described in job postings. We are committed to building a diverse, equitable, inclusive, and innovative company and we are looking for the BEST candidate for the job. That candidate may be one who comes from a less traditional background or may meet the qualifications in a different way. We would strongly encourage you to apply – especially if the reason you are the best candidate isn’t exactly as we describe it here.
It is the policy of Acadia to provide equal employment opportunities to all employees and employment applicants without regard to considerations of race, including related to hairstyle, color, religion or religious creed, sexual orientation, gender, gender identity, gender expression, gender transition, country of origin, ancestry, citizenship, age, physical or mental disability, genetic information, legally-protected medical condition or information, marital status, domestic partner status, family care status, military caregiver status, veteran or military status (including reserve status, National Guard status, and military service or obligation), status as a victim of domestic violence, sexual assault or stalking, enrollment in a public assistance program, or any basis protected under federal, state or local law.
As an equal opportunity employer, Acadia is committed to a diverse workforce. If you are a qualified individual with a disability or a disabled veteran, you have the right to request a reasonable accommodation. Furthermore, you may request additional support if you are unable or limited in your ability to use or access Acadia’s career website due to your disability, along with any accommodations throughout the interview process. To request or inquire about your reasonable accommodation, please complete our Reasonable Accommodation Request Form or contact us at [email protected] or 858-261-2923.
Please note that reasonable accommodations granted throughout the recruiting process are not guaranteed to be the same accommodation given if hired. A new request will need to be submitted for any ADA accommodations after starting employment.